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Monoclonal Antibody Against the Receptor for Advanced Glycation Endproducts
Scientists at NDSU have developed a monoclonal antibody that inhibits activation of the receptor for advanced glycation end products (RAGE). The antibody binds the V-domain to block activation of RAGE by its ligands. This antibody has delayed tumor growth in a xenograft melanoma model. The V-domain can bind multiple structurally and functionally diverse...
Published: 11/24/2025
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Inventor(s): Estelle Leclerc, Stefan Vetter
Keywords(s):
Category(s): Technologies > Biology & Medicine
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